Acid exposure can degrade many peptide sequences if left unprotected. Minor changes in acid levels often lead to decreased quality peptides when not properly buffered.
Optimal pH Levels for Various Peptides
Peptides typically remain stable near neutral pH. But certain amino acid derivatives can withstand slightly acidic conditions. This flexibility determines which application is suitable in a given laboratory study.
How to Mitigate Acid-Related Degradation
Use well-tested reagent buffers, maintain temperature control, and store in sealed vials. These steps preserve purity and reduce the chance of detrimental side reactions.